Activities of the Foundation

Since its establishment in 1988, the E.K. Frey – E. Werle Foundation has supported scientific conferences and symposia with nearly 600,000 US$ in total. The awards and laudation speeches have been presented by the former President of the LMU, Prof. Dr. Wulf Steinmann (1988-1995) and subsequently by Prof. Dr. Werner Müller-Esterl and Prof. Dr. Hans Fritz. Some of the laudatios have been published in Immunopharmacology 43, 91-95 (1999) and 32, 2-5 (1996) as well as in Agents & Actions, Suppl. 38/I, 8-17 (1992).

Recipients of the Awards

1988	International Symposium on the occasion of the 100th birthday anniversary of E.K. Frey: 'The Kallikrein-Kinin System in Health and Disease', Munich, Germany
	Medal	Ervin G. Erdös (USA)
	Prize	Gerd Bönner (Germany) & Walter Jauch (Germany)

1989	Symposium '20 Years of Research by SFB 51 and SFB 207 of LMU Munich' with Academic Celebration in the Aula of the LMU, Munich, Germany
	Medal	Robert Huber (Germany)
	Prize	Wolfram Bode (Germany)

1991	International Conference KININ '91 Munich, Germany
	Medal	John M. Stewart (USA)
	Prize	Carlos D. Figueroa (Chile) & Alvin H. Schmaier (USA)

1993	International Conference KININ '93 Brazil, Guarujá (Sao Paulo), Brazil
	Medal	Sergio H. Ferreira (Brazil)
	Prize	Kurt Jarnagin (USA) & David Proud (USA)

1994	International Conference on KININS, Montreal, Canada
	Medal	Domenico Regoli (Canada)
	Prize	Bernward A. Schoelkens (Germany)

1995	International Conference KININ '95 Denver, USA
	Medal	Mel Schachter (UK)
	Prize	Julie Chao (USA) & Lee Chao (USA)

1996	International Conference KININ '96 Durban, South Africa
	Medal	Kanti D. Bhoola (South Africa)

1997	Gordon Research Conference on Kallikreins and Kinins, Barga, Italy
	Medal	Harry S. Margolius (USA)
	Prize	François Alhenc-Gelas (France)

1998	International Conference KININ '98, Nara, Japan
	Medal	Hiroshi Maeda (Japan)
	Prize	Fredrik Leeb-Lundberg (USA, Sweden)
	Honorary Member	Sadaaki Iwanaga (Japan)

1998	3rd Symposium 'From Increased Energy Metabolism to Cardiac Hypertrophy and Failure', Baden-Baden, Germany
	Medal	Victor J. Dzau (USA)

2000	International Conference KININS 1925 - 2000 MUNICH, organized by the E.K. FREY – E. WERLE Foundation
	Honorary Members	Oscar A. Carretero (USA) Judith Clements (Australia) Robert W. Colman (USA) Alan W. Cuthbert (England) Günther Dietze (Germany) Lowell M. Greenbaum (USA) Sadaaki Iwanaga (Japan) Allen P. Kaplan (USA) Makoto Katori (Japan) Klaus Peter (Germany) Claudio A. M. Sampaio (Brazil) Kazuaki Shimamoto (Japan)

2002	International Conference KININ '02, Charleston, USA
	Medal	Hans Fritz (Germany)
	Prize	Fred Hess (USA)

2005	1st International Conference 'Exploring the Future of Local Vascular and Inflammatory Mediators', Lund, Sweden
	Medal	Rudi Busse (Germany)
	Prize	François Marceau (Canada)

2007	KININ 2007: 2nd International Conference 'Exploring the Future of Vascular and Inflammatory Mediators', Berlin, Germany
	Medal	Oliver Smithies (USA)
	Prize	João Pesquero (Brazil)

2007	2nd International Symposium on 'Kallikreins & Kallikrein-related Peptidases', Santorini Island, Greece
	Medal	Judith Clemens (Australia)

2007	5th General Meeting of the International Proteolysis Society, Patras, Greece
	Medal	Eleftherios Diamandis (Canada)

2008	43rd Annual Meeting of the German Diabetes Association, Munich, Germany
	Medal	Erik John Henriksen (USA)

2009	5th International Symposium on Peptide Receptors & KININ 2009, Québec City, Canada
	Medal	Werner Müller-Esterl (Germany) Oscar Carretero (USA)
	Prize	Nancy Brown (USA)

2009	3rd International Symposium on Kallikreins and Kallikrein-related Petidases, Munich, Germany
	Medal	Michael Blaber (USA)
	Prize	Andreas Scorilas (Greece)
	Young Investigator Award	Katerina Oikonomopoulou (Canada)

 

 

E.K. Frey – E. Werle Commemorative Gold Medalists

	Medalists	Major Topics
1988	Ervin Erdös USA	Peptide hormone cleaving enzymes Kininases
1989	Robert Huber Germany	Structures and functions of proteases and protease inhibitors
1991	John Stewart USA	Design and synthesis of kinin agonists and antagonists
1993	Sergio Ferreira Brazil	ACE inhibition by bradykinin potentiating peptides Antihypertensives and peripheral analgesics
1994	Domenico Regoli Canada	Receptor pharmacology of kinins and other neuropeptides
1995	Mel Schachter UK	Comparative pharmacology of bradykinin, kallidin and wasp kinin (KININ term introduced)
1996	Kanti Bhoola South Africa	Functional roles of kinins and their molecular mechanisms of action Localization of components of the KKS
1997	Harry Margolius USA	KKS in hypertension, diabetes, epithelial transport and central nervous system
1998	Hiroshi Maeda Japan	KKS in infectious diseases and inflammation Parasitic proteases and KKS
1999	Victor Dzau USA	Physiology and pathophysiology of the renin-angiotensin system
2002	Hans Fritz Germany	Structures, functions and biological roles of kallikreins, proteases and their inhibitors
2005	Rudi Busse Germany	Endothelium: Control of vascular tone and homeostasis (kinins, NO)
2007	Oliver Smithies USA	Gene targeting technology: Role of kinins and other cardiovascular hormones
2007	Judith Clements Australia	Gene locus of tissue kallikrein family KLK peptidases in hormone-dependent cancers
2007	Eleftherios Diamandis Canada	Tissue kallikrein gene family KLK peptidases as cancer biomarkers
2008	Eric Henriksen USA	Significance of the RAS und KKS in the modulation of insulin action in skeletal muskle tissue
2009	Werner Müller-Esterl Germany	Kininogens, kinin receptors, and ACE inhibitors: Structures and functions
2009	Oscar Carretero USA	KKS and RAS in blood pressure regulation, renal function, and organ damage
2009	Michael Blaber USA	KLK peptidases: Structural biology, enzymology and activation profiles

E.K. Frey - E. Werle Promotion Prize Recepients

	Recepients	Major Topics
1988	Gerd Bönner Germany	Renal KKS in arterial hypertony Clinical pharmacology of ACE inhibitors
	Karl-Walter Jauch Germany	Kinins & ACE inhibitors in regenerative metabolism
1989	Wolfram Bode Germany	Proteinases, inhibitors, substrates: Xray structures, molecular mechanism of interactions
1991	Carlos Figueroa Chile	Cellular localization of tissue-kallikreins and kininogens Role of the KKS in the inflammatory response
	Alvin H. Schmaier USA	Kininogens: Functions, reaction mechanisms, interactions with coagulant and inflammatory cells
1993	Kurt Jarnagin USA	The bradykinin receptor: Molecular biology and pharmacology
	David Proud USA, Canada	Role of kinins in the pathogenesis of allergic rhinitis as base for new therapeutic approaches
1994	Bernward Schölkens Germany	Clinical efficacy of bradykinin receptor antagonists Cardioprotective effects of ACE inhibitors
1995	Julie Chao USA	Kallistatin, a new member of the serpin superfamily: Biochemistry, molecular biology, physiological function
	Lee Chao USA	Tissue kallikrein genes: Cloning, characterization, regulation, targeting to animal models for therapeutic approaches
1997	François Alhenc-Gelas France	Cloning and function of ACE, ACE gene polymorphism ACE as a cardiovascular and renal risk factor
1998	Fredrik Leeb-Lundberg USA, Sweden	Kinin receptors: Ligand binding, intracellular trafficking Kinin stimulated cellular pathways
2002	Fred Hess USA	Mammalian kinin receptors: Cloning, expression, structural/functional characterization, gene targeting
2005	François Marceau Canada	Kinin receptors: Molecular architecture, functional role in patho/physiology, therapeutic potential
2007	João Pasquero Brazil	Molecular biology of kinin receptors Patho/physiology of the KKS in transgenic knockout animal models
2009	Nancy Brown USA	Cardiovascular effects of the KKS in humans in health and disease
2009	Andreas Scorilas Greece	Clinical relevance of KLK peptidases, novel cancer- and apoptosis-related genes

E.K. Frey - E. Werle Young Investigator Award

	Recepients	Major Topics
2009	Katerina Oikonomopoulou Canada	KLK peptidases: Expression in cancer and involvement in cell signalling